Shifter’s 16th issue, titled Pluripotential, presents scores, scripts, instructions, critical essays and more. Its title invokes a term that describes the innate ability of stem-cells to differentiate into almost any cell in the body in order to think through the possibility of criticality and cultural change through aesthetic strategies. This play between structural constraints and a potential for continuous change is seen in forms such as scores, scripts and instructions; and strategies including “detournement” and remix, which hold within them the potential to be performed and reconstituted in multiple ways.